Research Topics

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  • Quantitative Structure-Retention Relationships (QSRR).
  • Analytical chemistry: theory and applications of chromatography.
  • Chemometrics, bioinformatics, molecular modeling and rational basis of drug design.
  • Determination of lipophilicity and dissociation constant of drugs and other xenobiotics by chromatographic methods.
  • Assessment of affinity of drugs to biomacromolecules by liquid chromatography and capillary electrophoresis.
  • Biosensors in studies of drug-receptor interactions.
  • Neural networks in prediction of pharmacological and epidemiological effects of xenobiotics.
  • Molecular and submolecular characteristic of interaction of drugs with blood proteins and other biomolecules.
  • Imidazoline and alfa-adrenergic receptors in rats and humans.
  • Pharmacology of antiagregatory and antithrombotic drugs.
  • Proteomics and metabonomics.
  • Bioavailability of drugs, in particular: permeation through blood-brain barrier.